About treatment of idiopathic thrombocytopenic purpura (ITP).

نویسنده

  • Sinasi Ozsoylu
چکیده

Their treatment results with megadose methylprednisolone (MDMP) support fairly closely our complete remission results, though theirs was a retrospective evaluation. In our prospective, comparative study, antiplatelet antibodies were also determined3. Their 80% complete remission rate (mistakenly written as 66% in the text) with MDMP administration was much better than other therapeutic approaches (prednisolone and intravenous immunoglobulin [IVIG]) in the first month, though written as not significantly different. Similar to our results, complete improvement at one month was better in the untreated group compared to the prednisolone group, which we were the first to point out3. Surprisingly, the recurrence rate was found higher (22%) by the authors than shown by our results in which MDMP was given for a much longer (35 days) period iv. Recurrence rate and chronicity seemed to be related to the dose and the duration of MDMP treatment4.

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عنوان ژورنال:
  • The Turkish journal of pediatrics

دوره 50 2  شماره 

صفحات  -

تاریخ انتشار 2008